Editorial: X-linked retinoschisis: mechanisms and therapies

X-linked retinoschisis (XLRS) is the most common hereditary juvenile macular degeneration in males, resulting in significant vision impairment. Generally, disease progression is slow but can lead to consequential visual loss over time. Pathogenic variants in one gene (RS1) cause XLRS, making it an important clinical target for developing treatments.

This Research Topic features 7 original articles that address the natural history, mechanism, and possible treatment of XLRS.